Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | HTR3B | O95264 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046189 | 0.90 | OPRM1 (0.48) | MEN1KMT2AHTR3EHTR3BCHRNA7 | |
| SCHEMBL11051361 | 0.85 | SCN1A (0.59) | MEN1KMT2ASCN1ASCN2ASCN3A | |
| SCHEMBL27052723 | 0.84 | CHRM2 (0.52) | MEN1KMT2AHTR3EHTR3BCHRNA7 | |
| SCHEMBL11053024 | 0.84 | L3MBTL1 (0.57) | MEN1KMT2ACHRNA7SCN1ASCN2A | |
| SCHEMBL11067038 | 0.83 | HRH3 (0.52) | SCN1ASCN2ASCN3AGAATSHR | |
| SCHEMBL11044803 | 0.83 | SCN1A (0.53) | MEN1KMT2AOPRM1OPRD1SCN1A | |
| SCHEMBL11048109 | 0.83 | ALDH1A1 (0.43) | MEN1KMT2AOPRM1OPRD1SCN1A | |
| SCHEMBL11044959 | 0.82 | ALDH1A1 (0.53) | KMT2ACHRNA7GAA | |
| SCHEMBL11047716 | 0.79 | POLB (0.59) | MEN1KMT2ACHRM4CHRM3CHRM2 | |
| SCHEMBL10635659 | 0.79 | MEN1 (0.46) | MEN1KMT2AHTR3EHTR3BCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451473-A | 3,7-Diazabicyclo [3.3.1] nonanes having anti-arrhythmic activity | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-05-29 | — | — | US | claimed |
| US-4451473-A | 3,7-Diazabicyclo [3.3.1] nonanes having anti-arrhythmic activity | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-05-29 | — | — | US | disclosed |