Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.69 |
| ▸ | SHBG | P04278 | 6/20 | 0.69 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.69 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.69 |
| ▸ | BLM | P54132 | 3/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.69 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.68 |
| ▸ | PGR | P06401 | 4/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.68 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209282 | 0.91 | SHBG (0.65) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL8853536 | 0.91 | LMNA (0.72) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL8937171 | 0.91 | LMNA (0.72) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL3940460 | 0.90 | LMNA (0.73) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL4971448 | 0.90 | LMNA (0.73) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL11101324 | 0.90 | LMNA (0.71) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL13941349 | 0.89 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL260024 | 0.89 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL27048175 | 0.89 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL29766827 | 0.89 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482494-A | Process for preparing 17α-hydroxy-pregn-4-en-3,20-dione | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-11-13 | — | — | US | disclosed |
| EP-0063368-B1 | PROCESS FOR THE PREPARATION OF PREGN-4-ENE-3,20-DIONE DERIVATIVES AND 17-ALPHA-ETHYNYL-17-BETA-TRIFLUOROACETOXY-GON-4-ENE-3-ONE DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE LATTER COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-07-25 | — | — | EP | disclosed |
| US-4368160-A | Process for preparing 17α-hydroxy-pregn-4-en-3,20-dione derivatives | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1983-01-11 | — | — | US | disclosed |
| EP-0063368-A1 | Process for the preparation of pregn-4-ene-3,20-dione derivatives and 17-alpha-ethynyl-17-beta-trifluoroacetoxy-gon-4-ene-3-one derivatives, and pharmaceutical compositions containing the latter compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1982-10-27 | — | — | EP | disclosed |
| US-4102908-A | Process for the preparation of pregnane derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1978-07-25 | — | — | US | disclosed |