Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.72 |
| ▸ | SHBG | P04278 | 6/20 | 0.72 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.72 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.72 |
| ▸ | BLM | P54132 | 3/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.72 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.71 |
| ▸ | PGR | P06401 | 4/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.71 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.71 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853536 | 0.93 | LMNA (0.72) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL11101324 | 0.92 | LMNA (0.71) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL29766827 | 0.91 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL260024 | 0.91 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL27048175 | 0.91 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL11045530 | 0.91 | LMNA (0.69) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL260023 | 0.91 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL13941349 | 0.91 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL12666930 | 0.91 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 | |
| SCHEMBL10598120 | 0.91 | SHBG (0.67) | LMNASMN1; SMN2SHBGNR3C1SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506220-A | Anti-glaucomatous pharmaceutical composition and the process for obtaining them | LABORATOIRE THERAMEX SA (MC) | 1996-04-09 | — | — | US | disclosed |
| US-4102908-A | Process for the preparation of pregnane derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1978-07-25 | — | — | US | disclosed |