Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046764 | 0.88 | LMNA (0.51) | KMT2ALMNAPKMALDH1A1CYP3A4 | |
| SCHEMBL11046091 | 0.84 | KMT2A (0.57) | KMT2ALMNAPKMALDH1A1CYP3A4 | |
| SCHEMBL11054193 | 0.82 | KMT2A (0.41) | KMT2AALDH1A1CYP3A4MAPTTSHR | |
| SCHEMBL11115482 | 0.81 | LMNA (0.53) | KMT2ALMNAPKMALDH1A1CYP3A4 | |
| SCHEMBL11069090 | 0.80 | KMT2A (0.59) | KMT2ALMNAPKMALDH1A1CYP3A4 | |
| SCHEMBL11114298 | 0.78 | KMT2A (0.56) | KMT2APKMALDH1A1CYP3A4HSP90AA1 | |
| SCHEMBL11049367 | 0.77 | KMT2A (0.55) | KMT2AALDH1A1CYP3A4HSP90AA1MAPT | |
| SCHEMBL11071704 | 0.76 | LMNA (0.50) | KMT2ALMNAPKMALDH1A1CYP3A4 | |
| SCHEMBL2550587 | 0.76 | LMNA (0.67) | LMNAPKMALDH1A1CYP3A4CYP19A1 | |
| SCHEMBL10617937 | 0.76 | KMT2A (0.67) | KMT2ALMNAPKMALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117578-A2 | Azole-substituted alcohol derivatives | SHIONOGI & CO., LTD. (JP) | 1984-09-05 | — | — | EP | disclosed |