Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153294 | 0.85 | DHFR (0.43) | HTR1ATP53DHFRKCNH2CHRM2 | |
| SCHEMBL249154 | 0.83 | HTT (0.44) | HTR1ATP53DHFRKCNH2CHRM2 | |
| SCHEMBL8234142 | 0.81 | KCNH2 (0.44) | KCNH2ALDH1A1SIGMAR1HTTL3MBTL1 | |
| SCHEMBL24631166 | 0.81 | TP53 (0.39) | HTR1ATP53KCNH2CHRM2ADRA2A | |
| SCHEMBL4559051 | 0.80 | KCNH2 (0.46) | KCNH2ALDH1A1SIGMAR1HTTL3MBTL1 | |
| SCHEMBL1406224 | 0.80 | LIPG (0.46) | KCNH2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL7607872 | 0.80 | KCNH2 (0.46) | KCNH2ALDH1A1SIGMAR1HTTL3MBTL1 | |
| SCHEMBL986349 | 0.80 | KCNH2 (0.46) | KCNH2ALDH1A1SIGMAR1HTTL3MBTL1 | |
| SCHEMBL109304 | 0.80 | KCNH2 (0.46) | KCNH2ALDH1A1SIGMAR1HTTL3MBTL1 | |
| SCHEMBL15772306 | 0.80 | KCNH2 (0.43) | KCNH2ALDH1A1SIGMAR1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122989-A1 | Stabilized polyoxyalkylene polyether polyols and polyurethane foams prepared therefrom | ATLANTIC RICHFIELD COMPANY (US) | 1984-10-31 | — | — | EP | disclosed |