SCHEMBL7153294

SCHEMBL7153294

CCCN(c1ccccc1)c1ccccc1N(CCC)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 2/20 0.43
TP53 P04637 2/20 0.41
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
ESR1 P03372 1/20 0.39
TSHR P16473 2/20 0.38
ALDH1A1 P00352 1/20 0.38
GLA P06280 1/20 0.38
KCNH2 Q12809 2/20 0.37
KDM4E B2RXH2 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 1/20 0.37
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
NR3C2 P08235 1/20 0.37
CRHR1 P34998 1/20 0.37
CHRM2 P08172 1/20 0.36
HTR1A P08908 1/20 0.36
ADRA2A P08913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL158097 0.88 MTNR1A (0.48) DHFRTP53MTNR1AMTNR1BESR1
SCHEMBL6882135 0.86 HTR1A (0.43) DHFRTP53MTNR1AMTNR1BESR1
Hydrochloric Acid SCHEMBL10684893 0.86 MTNR1A (0.47) DHFRTP53MTNR1AMTNR1BESR1
Ammonia Solution, Strong SCHEMBL4595141 0.86 MTNR1A (0.47) DHFRTP53MTNR1AMTNR1BESR1
SCHEMBL7153293 0.86 MTNR1A (0.47) DHFRTP53MTNR1AMTNR1BESR1
SCHEMBL11046282 0.85 HTR1A (0.39) DHFRTP53MTNR1AMTNR1BESR1
SCHEMBL7151745 0.84 MTNR1A (0.43) DHFRTP53MTNR1AMTNR1BESR1
SCHEMBL25109184 0.83 DHFR (0.37) DHFRTP53MTNR1AMTNR1BESR1
SCHEMBL3702923 0.83 SIGMAR1 (0.46) DHFRTP53ALDH1A1L3MBTL1KMT2A
SCHEMBL30680184 0.82 MAPT (0.43) DHFRTP53MTNR1AMTNR1BTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6532098-B1 Sandwiched between two electrically conductive substrates at least one of which is transparent; benzidine or phenylenediamine compounds, acryloyl-modified polyalkylene oxide; viologen compound NIPPON MITSUBISHI OIL CORPORATION (JP) 2003-03-11 US claimed
US-6532098-B1 Sandwiched between two electrically conductive substrates at least one of which is transparent; benzidine or phenylenediamine compounds, acryloyl-modified polyalkylene oxide; viologen compound NIPPON MITSUBISHI OIL CORPORATION (JP) 2003-03-11 US disclosed