Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 7/20 | 0.45 |
| ▸ | CASP6 | P55212 | 2/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.35 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.35 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049888 | 0.92 | ENPP2 (0.52) | ENPP2CASP6CTDSP1APEX1NT5E | |
| SCHEMBL11053242 | 0.90 | ENPP2 (0.48) | ENPP2CASP6CTDSP1APEX1NT5E | |
| SCHEMBL11044357 | 0.90 | CASP6 (0.51) | ENPP2CASP6CTDSP1APEX1NT5E | |
| SCHEMBL11044421 | 0.87 | ENPP2 (0.49) | ENPP2CASP6CTDSP1APEX1NT5E | |
| SCHEMBL11058317 | 0.86 | APEX1 (0.57) | ENPP2CASP6CTDSP1APEX1NT5E | |
| SCHEMBL11054028 | 0.84 | ENPP2 (0.53) | ENPP2CASP6CTDSP1APEX1NT5E | |
| SCHEMBL11074599 | 0.84 | CASP6 (0.60) | ENPP2CASP6CTDSP1APEX1NT5E | |
| SCHEMBL11047462 | 0.84 | CASP6 (0.51) | ENPP2CASP6CTDSP1APEX1NT5E | |
| SCHEMBL11044448 | 0.83 | ENPP2 (0.49) | ENPP2CASP6CTDSP1APEX1NT5E | |
| SCHEMBL11046533 | 0.83 | CASP6 (0.45) | ENPP2CASP6CTDSP1APEX1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473498-A | Water-soluble, fiber-reactive organic dyestuffs containing a β-chloro-ethylsulfonyl-methyl-benzoic acid amide group | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |