Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24965972 | 0.79 | TSHR (0.48) | LMNAOGATAAR1TSHRFAAH | |
| SCHEMBL11045989 | 0.74 | OGA (0.33) | LMNAOGATAAR1DRD1PDE4D | |
| SCHEMBL11049138 | 0.72 | OGA (0.32) | LMNAOGADRD1 | |
| SCHEMBL11047925 | 0.71 | PTPN1 (0.32) | LMNAOGADRD1 | |
| SCHEMBL7277950 | 0.71 | FAAH (0.45) | TAAR1FAAH | |
| SCHEMBL11047003 | 0.68 | FAAH (0.44) | TSHRFAAHMEN1KMT2A | |
| SCHEMBL5262180 | 0.67 | TSHR (0.45) | LMNATAAR1TSHRFAAHPOLB | |
| SCHEMBL712254 | 0.67 | TSHR (0.48) | LMNATAAR1TSHRDRD1POLB | |
| SCHEMBL28063722 | 0.66 | TSHR (0.44) | LMNATAAR1TSHRFAAHPOLB | |
| SCHEMBL713523 | 0.66 | TSHR (0.52) | LMNATAAR1TSHRDRD1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482730-A | Synthesis of dioxabicyclo[3.2.1]octanes and oxepanes | ORTHO PHARMACEUTICAL CORPORATION (US) | 1984-11-13 | — | — | US | disclosed |
| US-4387234-A | Synthesis of dioxabicyclo[3.2.1]octanes and oxepanes | ORTHO PHARMACEUTICAL CORPORATION (US) | 1983-06-07 | — | — | US | disclosed |
| EP-0012622-B1 | 1-TOSLOXY-2,2-ETHYLENEDIOXY-6,10-DIMETHYL UNDECANES AND UNDECENES, PROCESS FOR THE PREPARATION OF 2S*,3R*-3-BENZYLOXY-6,6-ETHYLENE DIOXY-2-METHYL-2-(5'-HYDROXY-4'-METHYLPENTYL)-OXEPANE, AND USE OF THE LATTER FOR THE PREPARATION OF OXEPAN-3-OL DERIVATIVES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1982-12-15 | — | — | EP | disclosed |
| US-4322353-A | Synthesis of dioxabicyclo(3.2.1)octanes and oxepanes | ORTHO PHARMACEUTICAL CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| EP-0038696-A2 | Synthesis of dioxabicyclo(3.2.1.)octanes and oxepanes | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-10-28 | — | — | EP | disclosed |
| US-4256644-A | 3-BENZYLOXY-6,6-ETHYLENEDIOXY-2-METHYL-2-(5-HYDROXY-4 -METHYLPENTYL)OXEPANE MADE BY A MULTISTEP PROCESS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| EP-0012622-A2 | 1-Tosloxy-2,2-ethylenedioxy-6,10-dimethyl undecanes and undecenes, process for the preparation of 2S*,3R*-3-benzyloxy-6,6-ethylene dioxy-2-methyl-2-(5'-hydroxy-4'-methylpentyl)-oxepane, and use of the latter for the preparation of oxepan-3-ol derivatives | ORTHO PHARMACEUTICAL CORPORATION (US) | 1980-06-25 | — | — | EP | disclosed |
| US-4188328-A | Chemical intermediates in the preparation of oxepane compounds | ORTHO PHARMACEUTICAL CORPORATION (US) | 1980-02-12 | — | — | US | disclosed |