Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11050852 | 0.90 | ALDH1A1 (0.45) | KDM4ENPC1ALDH1A1MAPTFBP1 | |
| SCHEMBL11044877 | 0.89 | LMNA (0.46) | KDM4ENPC1ALDH1A1MAPTLMNA | |
| SCHEMBL11123789 | 0.86 | KDM4E (0.45) | KDM4ENPC1ALDH1A1MAPTFBP1 | |
| SCHEMBL11052432 | 0.85 | ALDH1A1 (0.48) | KDM4ENPC1ALDH1A1MAPTFBP1 | |
| SCHEMBL11046006 | 0.84 | GAA (0.55) | KDM4ENPC1ALDH1A1MAPTGAA | |
| SCHEMBL11047395 | 0.83 | ALDH1A1 (0.45) | KDM4ENPC1ALDH1A1MAPTFBP1 | |
| SCHEMBL11045303 | 0.83 | TSHR (0.49) | KDM4ENPC1ALDH1A1MAPTGAA | |
| SCHEMBL11124648 | 0.81 | KDM4E (0.41) | KDM4ENPC1ALDH1A1MAPTFBP1 | |
| SCHEMBL11637413 | 0.81 | FBP1 (0.55) | KDM4ENPC1ALDH1A1MAPTFBP1 | |
| SCHEMBL10888753 | 0.80 | KDM4E (0.45) | KDM4ENPC1ALDH1A1MAPTFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044209-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-31 | — | — | EP | claimed |
| US-4348220-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-07 | — | — | US | claimed |
| EP-0044209-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-31 | — | — | EP | disclosed |
| US-4424377-A | HERBICIDES | E. I. DU PONT DE NEMOURS & CO. (US) | 1984-01-03 | — | — | US | disclosed |
| US-4348220-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0044209-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-20 | — | — | EP | disclosed |