SCHEMBL11047196

SCHEMBL11047196

CC=Cc1ccccc1CBr

nearest known ligand 0.32

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.32
TRPA1 O75762 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
PTGER3 P43115 2/20 0.32
PTGER2 P43116 2/20 0.32
PTGER4 P35408 1/20 0.32
TBXA2R P21731 1/20 0.31
PTGDR Q13258 1/20 0.31
CDK4 P11802 1/20 0.30
CCND1 P24385 1/20 0.30
NFE2L2 Q16236 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
NFKB1 P19838 1/20 0.30
CYP2C19 P33261 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19188151 0.80 CHAT (0.40) MEN1KMT2APTGER3PTGER2PTGER4
SCHEMBL9494233 0.80 CHAT (0.40) MEN1KMT2APTGER3PTGER2PTGER4
SCHEMBL9494239 0.80 CHAT (0.40) MEN1KMT2APTGER3PTGER2PTGER4
SCHEMBL31094912 0.80 CHAT (0.40) MEN1KMT2APTGER3PTGER2PTGER4
SCHEMBL18683426 0.79 TSHR (0.34) TSHRTRPA1ALDH1A1PTGER3PTGER2
SCHEMBL31348024 0.79 GABRA1 (0.45) MEN1KMT2APTGER3PTGER2PTGER4
SCHEMBL17160012 0.79 GABRA1 (0.45) MEN1KMT2APTGER3PTGER2PTGER4
SCHEMBL7959776 0.78 PNMT (0.41) MEN1KMT2APTGER3PTGER2PTGER4
SCHEMBL7959778 0.78 PNMT (0.41) MEN1KMT2APTGER3PTGER2PTGER4
SCHEMBL12429139 0.78 MEN1 (0.32) ALDH1A1MEN1KMT2APTGER3PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108368001-A Olefin metathesis catalyst 优美科股份公司及两合公司 2018-08-03 CN disclosed
EP-0025599-B1 BENZOPYRAN COMPOUNDS, USEFUL AS CHEMOTHERAPEUTIC AGENTS THE WELLCOME FOUNDATION LIMITED (GB) 1984-12-19 EP disclosed
US-4452991-A OR BENZO(B)INDENO (2,1-E) PYRANS OR BENZO(C)XANTHENES BATCHELOR JOHN F (GB) 1984-06-05 US disclosed