Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.61 |
| ▸ | HTR3B | O95264 | 2/20 | 0.61 |
| ▸ | HTR3A | P46098 | 2/20 | 0.61 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.61 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | F13A1 | P00488 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167193 | 0.94 | MEN1 (0.71) | MEN1KMT2AMAPTLMNAHTT | |
| Ammonia Solution, Strong SCHEMBL28790660 | 0.93 | MEN1 (0.69) | MEN1KMT2AMAPTLMNAHTT | |
| O-Xylene SCHEMBL11044886 | 0.88 | MEN1 (0.59) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL357999 | 0.83 | MEN1 (0.71) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL3690365 | 0.80 | MAPT (0.59) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL7173339 | 0.80 | MEN1 (0.67) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL8532903 | 0.79 | ALDH1A1 (0.67) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL2682054 | 0.79 | KMT2A (1.00) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL4108214 | 0.78 | MEN1 (0.59) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11449846 | 0.78 | IDO1 (0.66) | MEN1KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31550-E | N-(2-Chloro-4-pyridyl) ureas | Shudo, Koichi (JP) | 1984-04-10 | — | — | US | disclosed |