Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL20610167 | 0.93 | TP53 (0.53) | TP53SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL377291 | 0.90 | TP53 (0.56) | TP53SLC34A1LMNA | |
| Phosphoric Acid SCHEMBL11590142 | 0.87 | TP53 (0.53) | TP53SLC34A1LMNA | |
| Phosphoric Acid SCHEMBL20610254 | 0.87 | TP53 (0.53) | TP53SLC34A1LMNA | |
| Phosphoric Acid SCHEMBL6739275 | 0.77 | TP53 (0.43) | TP53LMNA | |
| Glycerin SCHEMBL28665884 | 0.75 | LMNA (0.53) | SLC34A1KDM4ETHRBCYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL16926985 | 0.72 | SLC34A1 (0.57) | SLC34A1KDM4EMMP2THRBMAPK1 | |
| Bicarbonate SCHEMBL2938935 | 0.72 | TP53 (0.59) | TP53LMNA | |
| Sulfurous Acid SCHEMBL11518322 | 0.69 | TP53 (0.56) | TP53 | |
| SCHEMBL22749159 | 0.69 | TP53 (0.56) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11987661-B2 | Modified polymer polyols | REPSOL, S.A. (ES) | 2024-05-21 | — | — | US | claimed |
| EP-3649164-B1 | MODIFIED POLYMER POLYOLS | REPSOL SA (ES) | 2021-09-08 | — | — | EP | claimed |
| US-20210130528-A1 | MODIFIED POLYMER POLYOLS | REPSOL, S.A. (ES) | 2021-05-06 | — | — | US | claimed |
| EP-3649164-A1 | MODIFIED POLYMER POLYOLS | Repsol, S.A. (ES) | 2020-05-13 | — | — | EP | claimed |
| WO-2019008140-A1 | MODIFIED POLYMER POLYOLS | REPSOL, S.A. (ES) | 2019-01-10 | — | — | WO | claimed |
| EP-4619451-A1 | MODIFIED POLYMER POLYOLS | Repsol, S.A. (ES) | 2025-09-24 | — | — | EP | disclosed |
| WO-2025073830-A1 | STABLE MODIFIED POLYMER POLYOL DISPERSIONS | REPSOL, S.A. (ES) | 2025-04-10 | — | — | WO | disclosed |
| WO-2024105080-A1 | MODIFIED POLYMER POLYOLS | REPSOL, S.A. (ES) | 2024-05-23 | — | — | WO | disclosed |
| US-11987661-B2 | Modified polymer polyols | REPSOL, S.A. (ES) | 2024-05-21 | — | — | US | disclosed |
| US-11912812-B2 | Stable modified polymer polyol dispersions | REPSOL, S.A. (ES) | 2024-02-27 | — | — | US | disclosed |
| EP-3838959-B1 | STABLE MODIFIED POLYMER POLYOL DISPERSIONS | REPSOL SA (ES) | 2023-10-25 | — | — | EP | disclosed |
| EP-3649164-B1 | MODIFIED POLYMER POLYOLS | REPSOL SA (ES) | 2021-09-08 | — | — | EP | disclosed |
| EP-3838962-A1 | STABLE MODIFIED POLYMER POLYOL DISPERSIONS | Repsol, S.A. (ES) | 2021-06-23 | — | — | EP | disclosed |
| EP-3838959-A1 | STABLE MODIFIED POLYMER POLYOL DISPERSIONS | Repsol, S.A. (ES) | 2021-06-23 | — | — | EP | disclosed |
| CN-113004488-A | Stable modified polymer polyol dispersions | 雷普索尔有限公司 | 2021-06-22 | — | — | CN | disclosed |
| CN-113004511-A | Stable modified polymer polyol dispersions | 雷普索尔有限公司 | 2021-06-22 | — | — | CN | disclosed |
| US-20210130528-A1 | MODIFIED POLYMER POLYOLS | REPSOL, S.A. (ES) | 2021-05-06 | — | — | US | disclosed |
| EP-3649164-A1 | MODIFIED POLYMER POLYOLS | Repsol, S.A. (ES) | 2020-05-13 | — | — | EP | disclosed |
| WO-2019008140-A1 | MODIFIED POLYMER POLYOLS | REPSOL, S.A. (ES) | 2019-01-10 | — | — | WO | disclosed |
| US-4483689-A | GRAFTING, CURING OF N-METHYLOLACRYLAMIDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1984-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912812-B2 | Stable modified polymer polyol dispersions | PUF60, PCBP1, PARG | TP53 2690/4885SLC34A1 3994/4885KDM4E 2545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.