Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 5/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | CD44 | P16070 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046386 | 0.86 | HTR3A (0.48) | HTR3AHRH2HRH1HRH4HRH3 | |
| SCHEMBL11047575 | 0.82 | TAAR1 (0.51) | HTR3AHRH2HRH1HRH4HRH3 | |
| SCHEMBL9519546 | 0.76 | GABRR1 (0.41) | HTR3AHRH2HRH1HRH4HRH3 | |
| SCHEMBL644231 | 0.75 | HTR3A (0.59) | HTR3AHRH2HRH1HRH4HRH3 | |
| SCHEMBL10743073 | 0.75 | HRH2 (0.53) | HTR3AHRH2HRH1HRH4HRH3 | |
| SCHEMBL12301245 | 0.74 | HTR3A (0.44) | HTR3AHRH2HRH1HRH4HRH3 | |
| SCHEMBL3306785 | 0.73 | ESR1 (0.47) | TAAR1SMN1; SMN2 | |
| SCHEMBL10885778 | 0.73 | TP53 (0.47) | HRH2HRH1HRH4HRH3TDP1 | |
| SCHEMBL642976 | 0.73 | HTR3A (0.54) | HTR3AHRH2HRH1HRH4HRH3 | |
| SCHEMBL10741491 | 0.72 | HRH2 (0.55) | HTR3AHRH2HRH1HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443466-A | DIURETICS, SEDATIVES, ANALGESICS | Farmos-Yhtyma OY (Farmos Group Ltd.) (FI) | 1984-04-17 | — | — | US | claimed |
| EP-0024829-B1 | 4-BENZYL- AND 4-BENZOYLIMIDAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Farmos-Yhtyma Oy (FI) | 1984-04-25 | — | — | EP | disclosed |
| US-4443466-A | DIURETICS, SEDATIVES, ANALGESICS | Farmos-Yhtyma OY (Farmos Group Ltd.) (FI) | 1984-04-17 | — | — | US | disclosed |