Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 2/20 | 0.51 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.51 |
| ▸ | RXRA | P19793 | 5/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046403 | 0.83 | CPB1 (0.54) | CPB1CPB2RXRAGRIN1GRIN2B | |
| SCHEMBL20162954 | 0.80 | NOTUM (0.40) | CPB1CPB2PI4KAPI4K2BPI4K2A | |
| SCHEMBL30037434 | 0.80 | NOTUM (0.40) | CPB1CPB2PI4KAPI4K2BPI4K2A | |
| SCHEMBL29563229 | 0.80 | KDM4E (0.40) | CPB1CPB2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL15633080 | 0.77 | CYP2E1 (0.47) | CPB1CPB2FLT3GSK3BPI4KA | |
| SCHEMBL27163123 | 0.75 | CPB2 (0.47) | CPB1CPB2 | |
| SCHEMBL28734546 | 0.72 | P2RX3 (0.37) | ELANE | |
| SCHEMBL27786860 | 0.71 | CPB2 (0.47) | CPB1CPB2ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL28073106 | 0.71 | CPB1 (0.43) | CPB1CPB2FLT3GSK3BPI4KA | |
| SCHEMBL27786917 | 0.71 | KDM4E (0.55) | CPB1CPB2ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024829-B1 | 4-BENZYL- AND 4-BENZOYLIMIDAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Farmos-Yhtyma Oy (FI) | 1984-04-25 | — | — | EP | disclosed |
| US-4443466-A | DIURETICS, SEDATIVES, ANALGESICS | Farmos-Yhtyma OY (Farmos Group Ltd.) (FI) | 1984-04-17 | — | — | US | disclosed |