Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | ATIC | P31939 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.37 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.36 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11047990 | 1.00 | POLB (0.40) | POLBCYP2D6CYP1A2CYP2C9RPS6KA3 | |
| SCHEMBL13557906 | 0.84 | CYP1A2 (0.40) | POLBCYP2D6CYP1A2CYP2C9RPS6KA3 | |
| SCHEMBL14373601 | 0.84 | CYP1A2 (0.40) | POLBCYP2D6CYP1A2CYP2C9RPS6KA3 | |
| SCHEMBL15298975 | 0.81 | ALOX5 (0.46) | POLBCYP2D6CYP1A2CYP2C9RPS6KA3 | |
| SCHEMBL13557905 | 0.78 | CYP2C19 (0.55) | POLBCYP2D6CYP1A2CYP2C9RPS6KA3 | |
| SCHEMBL21469257 | 0.77 | POLB (0.44) | POLBCYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12947973 | 0.76 | CYP1A2 (0.47) | POLBCYP2D6CYP1A2CYP2C9RPS6KA3 | |
| SCHEMBL28579797 | 0.75 | ATIC (0.66) | CYP1A2CYP2C9ATICNPC1MAPT | |
| SCHEMBL13915906 | 0.71 | ALDH1A1 (0.44) | CYP1A2CYP2C9CYP2C19PHLPP2NPC1 | |
| SCHEMBL13082625 | 0.71 | CYP1A2 (0.35) | POLBCYP2D6CYP1A2CYP2C9RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464281-A | PRECONDITIONED BY AIR FLOW | LEVER BROTHERS COMPANY (US) | 1984-08-07 | — | — | US | disclosed |