Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29734579 | 0.83 | SMN1; SMN2 (0.36) | SMN1; SMN2RAB9ANPC1LMNAHPGD | |
| SCHEMBL4758404 | 0.83 | SMN1; SMN2 (0.36) | SMN1; SMN2RAB9ANPC1LMNAHPGD | |
| SCHEMBL10794515 | 0.83 | THRB (0.35) | — | |
| SCHEMBL8063043 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9ANPC1LMNAHPGD | |
| SCHEMBL5085699 | 0.77 | GRM4 (0.41) | SMN1; SMN2RAB9ANPC1LMNAHPGD | |
| SCHEMBL4789470 | 0.75 | THRB (0.40) | HPGDALDH1A1MAPT | |
| SCHEMBL29904785 | 0.74 | THRB (0.51) | SMN1; SMN2RAB9ANPC1LMNAHPGD | |
| SCHEMBL446746 | 0.74 | THRB (0.51) | SMN1; SMN2RAB9ANPC1LMNAHPGD | |
| SCHEMBL18492245 | 0.74 | KDM4E (0.52) | SMN1; SMN2LMNAALDH1A1TDP1 | |
| SCHEMBL10489299 | 0.74 | LMNA (0.52) | SMN1; SMN2LMNAALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487904-A | Urethanized acrylic resin material for plastic lens and lens composed thereof | TORAY INDUSTRIES, INC. (JP) | 1984-12-11 | — | — | US | disclosed |