SCHEMBL1104808

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15315974	0.80	ESR1 (0.55)	MAPK1HTTTSHRCYP1A2ALDH1A1
	SCHEMBL19275969	0.79	MAPK1 (0.59)	MAPK1HTTTSHRPIK3CDPIK3CA
	SCHEMBL28915920	0.79	SMN1; SMN2 (0.50)	MAPK1HTTCYP1A2ALDH1A1HRH3
	SCHEMBL18355560	0.78	CYP1A2 (0.52)	MAPK1HTTCYP1A2ALDH1A1HRH3
	SCHEMBL63585	0.77	HTT (0.71)	MAPK1HTTTSHRPIK3CDPIK3CA
	SCHEMBL13052907	0.77	HTT (0.61)	MAPK1HTTTSHRPIK3CDPIK3CA
	SCHEMBL16739752	0.77	MAPK1 (0.56)	MAPK1HTTTSHRPIK3CDPIK3CA
	SCHEMBL14743278	0.77	HRH3 (0.46)	MAPK1HTTCYP1A2ALDH1A1HRH3
	SCHEMBL540845	0.76	MAPK1 (0.59)	MAPK1HTTTSHRPIK3CDPIK3CA
	SCHEMBL13052926	0.76	HTT (0.69)	MAPK1HTTTSHRPIK3CDPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.