Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26705241 | 0.80 | PTPN1 (0.64) | PTPN2PTPN1PTPN6PTPN11HTT | |
| SCHEMBL11045277 | 0.75 | MEN1 (0.56) | GAAKMT2ACHRNA7TSHR | |
| SCHEMBL27105237 | 0.72 | PTPN2 (0.58) | PTPN2PTPN1PTPN6PTPN11HTT | |
| SCHEMBL24278560 | 0.72 | PTPN2 (0.57) | PTPN2PTPN1PTPN6PTPN11HTT | |
| SCHEMBL11046243 | 0.72 | TSHR (0.49) | KMT2ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL11048109 | 0.72 | ALDH1A1 (0.43) | GAAKMT2AALDH1A1 | |
| SCHEMBL11044959 | 0.71 | ALDH1A1 (0.53) | GAAKMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL24278832 | 0.71 | PTPN1 (0.54) | PTPN2PTPN1PTPN6PTPN11HTT | |
| SCHEMBL11051361 | 0.71 | SCN1A (0.59) | GAAKMT2AMAPTCYP1A2ALDH1A1 | |
| SCHEMBL24278718 | 0.71 | PTPN2 (0.56) | PTPN2PTPN1PTPN6PTPN11HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451473-A | 3,7-Diazabicyclo [3.3.1] nonanes having anti-arrhythmic activity | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-05-29 | — | — | US | disclosed |