Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417591 | 0.82 | TSHR (0.51) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL15147383 | 0.77 | CHRM3 (0.60) | ALDH1A1CHRM4CHRM3SMN1; SMN2KMT2A | |
| SCHEMBL15147380 | 0.77 | CHRM3 (0.60) | ALDH1A1CHRM4CHRM3SMN1; SMN2KMT2A | |
| SCHEMBL11045277 | 0.76 | MEN1 (0.56) | TSHRCHRM4CHRM3KMT2A | |
| SCHEMBL15080870 | 0.76 | TSHR (0.49) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL13266074 | 0.76 | ALDH1A1 (0.64) | ALDH1A1CHRM4CHRM3SMN1; SMN2KMT2A | |
| SCHEMBL15147382 | 0.74 | CYP2D6 (0.61) | ALDH1A1L3MBTL1CHRM4CHRM3SMN1; SMN2 | |
| SCHEMBL11048034 | 0.72 | CTSL (0.46) | — | |
| SCHEMBL22567784 | 0.72 | FAAH (0.47) | TSHRALDH1A1L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL11048124 | 0.72 | PTPN2 (0.56) | TSHRALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451473-A | 3,7-Diazabicyclo [3.3.1] nonanes having anti-arrhythmic activity | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-05-29 | — | — | US | disclosed |