SCHEMBL11048259

SCHEMBL11048259

C=CC[C@H]1CC[C@H](C2CCCCC2)CC1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
NOS1 P29475 4/20 0.37
NOS2 P35228 4/20 0.37
NOS3 P29474 2/20 0.37
ALOX5 P09917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1703059 1.00 ALDH1A1 (0.38) ALDH1A1NOS1NOS2NOS3ALOX5
Bicarbonate SCHEMBL11381268 0.90 HSD11B1 (0.33) ALDH1A1NOS1NOS2NOS3ALOX5
SCHEMBL2502334 0.85 NOS1 (0.42) ALDH1A1NOS1NOS2NOS3
SCHEMBL2499186 0.85 NOS1 (0.42) ALDH1A1NOS1NOS2NOS3
SCHEMBL89025 0.85
Cyclohexane SCHEMBL3694033 0.85 NOS1 (0.42) ALDH1A1NOS1NOS2NOS3
SCHEMBL7063115 0.85 NOS1 (0.42) ALDH1A1NOS1NOS2NOS3
SCHEMBL7740961 0.85 NOS1 (0.42) ALDH1A1NOS1NOS2NOS3
SCHEMBL2500447 0.85 NOS1 (0.42) ALDH1A1NOS1NOS2NOS3
SCHEMBL28837982 0.85 NOS1 (0.42) NOS1NOS2NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59095230-A None JP disclosed
JP-58170734-A None JP disclosed
JP-S5995230-A LIQUID CRYSTAL COMPOUND HAVING METHOXY GROUP AT SIDE CHAIN CHISSO CORP 1984-06-01 JP disclosed
JP-S58170734-A 4-(TRANS-4'-(TRANS-4\"-ALKYLCYCLOHEXYL)CYCLOHEXYL)-BENZOIC ACID 4-HALOGENOPHENYL ESTER CHISSO CORP 1983-10-07 JP disclosed