Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.54 |
| ▸ | FNTA | P49354 | 7/20 | 0.50 |
| ▸ | FNTB | P49356 | 7/20 | 0.50 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10806681 | 0.79 | FNTA (0.44) | FNTAFNTBMAPK10PADI4IDO1 | |
| SCHEMBL11205807 | 0.77 | TAAR1 (0.43) | PADI4 | |
| SCHEMBL11048258 | 0.75 | FNTA (0.51) | FNTAFNTBVKORC1PKMMAPK10 | |
| SCHEMBL11049464 | 0.74 | TBXAS1 (0.56) | TBXAS1 | |
| SCHEMBL8539967 | 0.73 | TBXAS1 (0.50) | TBXAS1 | |
| SCHEMBL8539971 | 0.73 | TBXAS1 (0.50) | TBXAS1 | |
| SCHEMBL10806849 | 0.73 | ATM (0.54) | — | |
| SCHEMBL7373958 | 0.71 | ALDH1A1 (0.54) | — | |
| SCHEMBL10658479 | 0.71 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL10658490 | 0.71 | TBXAS1 (1.00) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451472-A | ANTITHROMBOSIS AND ANTIISCHEMIC AGENTS, AND TREATMENT OF VASCULAR COMPLICATIONS OF DIAMETES | PFIZER INC. (US) | 1984-05-29 | — | — | US | disclosed |
| US-4451472-A | ANTITHROMBOSIS AND ANTIISCHEMIC AGENTS, AND TREATMENT OF VASCULAR COMPLICATIONS OF DIAMETES | PFIZER INC. (US) | 1984-05-29 | — | — | US | disclosed |