SCHEMBL11048264

SCHEMBL11048264

CC1CNN(c2ccccc2)C1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.47
G6PD P11413 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ALOX5 P09917 3/20 0.40
POLB P06746 2/20 0.40
MAOA P21397 1/20 0.40
ALDH1A1 P00352 6/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
MAPT P10636 4/20 0.39
ALOX12 P18054 3/20 0.39
LMNA P02545 2/20 0.39
KDM4E B2RXH2 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
LOX P28300 1/20 0.39
LOXL3 P58215 1/20 0.39
LOXL4 Q96JB6 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9597146 0.78 ALDH1A1 (0.39) GAAG6PDL3MBTL1MEN1KMT2A
SCHEMBL10961845 0.75 GAA (0.41) GAAG6PDL3MBTL1MEN1KMT2A
SCHEMBL11435739 0.75 MAPK1 (0.39) GAAG6PDL3MBTL1KMT2AALOX5
SCHEMBL8649720 0.68 ALDH1A1 (0.43) GAAG6PDL3MBTL1MEN1KMT2A
SCHEMBL6731377 0.68 GAA (0.41) GAAG6PDL3MBTL1MEN1KMT2A
SCHEMBL17290760 0.68 ALDH1A1 (0.50) GAAG6PDL3MBTL1MEN1KMT2A
SCHEMBL266004 0.68 MEN1 (0.50) GAAG6PDL3MBTL1MEN1KMT2A
SCHEMBL12015718 0.68 MEN1 (0.50) GAAG6PDL3MBTL1MEN1KMT2A
SCHEMBL11420273 0.67 PABPC1 (0.41) GAAG6PDL3MBTL1MEN1KMT2A
SCHEMBL8089001 0.67 ALOX5 (0.44) GAAG6PDL3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4431659-A 1-(Aryl)thiocarbamoyl-2-(aryl)-3-pyrazolidinones and their nematicidal use FMC CORPORATION (US) 1984-02-14 US disclosed