SCHEMBL110483

SCHEMBL110483

C=C(C)C(=O)NCCCNC

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
MAPK1 P28482 1/20 0.39
HIF1A Q16665 1/20 0.39
KISS1R Q969F8 1/20 0.36
TGFBR1 P36897 1/20 0.34
PAOX Q6QHF9 3/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ADRA1A P35348 1/20 0.32
ACHE P22303 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
EPHX1 P07099 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28093970 0.98 KDM4E (0.38) KDM4EMAPK1HIF1AKISS1RTGFBR1
SCHEMBL109677 0.96 KDM4E (0.44) KDM4EMAPK1HIF1AKISS1RTGFBR1
SCHEMBL4324661 0.94 KDM4E (0.48) KDM4EMAPK1HIF1APAOXMEN1
SCHEMBL4330261 0.94 KDM4E (0.48) KDM4EMAPK1HIF1APAOXMEN1
Butane SCHEMBL22264054 0.92 PAOX (0.36) KDM4EMAPK1HIF1AKISS1RPAOX
Hydrochloric Acid SCHEMBL30637247 0.92 KDM4E (0.46) KDM4EMAPK1HIF1APAOXMEN1
Iodide SCHEMBL30637250 0.92 KDM4E (0.46) KDM4EMAPK1HIF1APAOXMEN1
SCHEMBL632876 0.91 KDM4E (0.46) KDM4EMAPK1HIF1ATGFBR1PAOX
SCHEMBL16309325 0.89 KDM4E (0.44) KDM4EMAPK1HIF1ATGFBR1PAOX
SCHEMBL112305 0.86 TGFBR1 (0.36) KDM4EMAPK1HIF1AKISS1RTGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 402 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4076916-B1 WETTABLE SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-06-12 EP claimed
EP-4146461-B1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-03-13 EP claimed
EP-4118134-B1 PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS ALCON INC (CH) 2024-02-28 EP claimed
EP-3802080-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-07-19 EP claimed
WO-2018046419-A1 ACCELERATION OF THE DRYING OF LAUNDRY HENKEL AG & CO. KGAA (DE) 2018-03-15 WO claimed
CN-105111378-B A kind of cationic polymer Grafted Nano-scale avicel cellulose and its preparation method and application 赵迎辉 2018-01-09 CN claimed
CN-105709705-A Molecular imprinting adsorbent for eliminating blood bilirubin and preparation method thereof 佛山市博新生物科技有限公司 2016-06-29 CN claimed
US-8524111-B2 CMP abrasive slurry for polishing insulation film, polishing method, and semiconductor electronic part polished by the polishing method HITACHI CHEMICAL COMPANY, LTD. (JP) 2013-09-03 US claimed
US-7700540-B2 Hard surface cleaning composition THE CLOROX COMPANY (US) 2010-04-20 US claimed
US-20090118150-A1 Process for Preparing Polymers and Compositions Thereof THE LUBRIZOL CORPORATION 2009-05-07 US claimed
US-20070099816-A1 Hard Surface Cleaning Composition THE CLOROX COMPANY 2007-05-03 US claimed
EP-1720407-A1 FORMULATION FOR SEED TREATMENT COMPRISING POLYMERIC STICKERS BASF AKTIENGESELLSCHAFT (DE) 2006-11-15 EP claimed
EP-1656111-A1 COSMETIC AND PHARMACEUTICAL SUBSTANCES BASED ON POLYELECTROLYTE COMPLEXES BASF AKTIENGESELLSCHAFT (DE) 2006-05-17 EP claimed
WO-2005077170-A1 FORMULATION FOR SEED TREATMENT COMPRISING POLYMERIC STICKERS BASF AKTIENGESELLSCHAFT (DE) 2005-08-25 WO claimed
US-20050084469-A1 Cationic polymers and the use thereof in cosmetic formulations BASF AKTIENGESELLSCHAFT (DE) 2005-04-21 US claimed
WO-2005004821-A1 COSMETIC AND PHARMACEUTICAL SUBSTANCES BASED ON POLYELECTROLYTE COMPLEXES BASF AKTIENGESELLSCHAFT (DE) 2005-01-20 WO claimed
EP-1490016-A1 CATIONIC POLYMERS AND THE USE THEREOF IN COSMETIC FORMULATIONS BASF AKTIENGESELLSCHAFT (DE) 2004-12-29 EP claimed
WO-2004055081-A2 COMPOSITION FOR COATING KERATIN FIBRES, COMPRISING A DISPERSION OF POLYMER PARTICLES L'OREAL (FR) 2004-07-01 WO claimed
WO-2003080001-A1 CATIONIC POLYMERS AND THE USE THEREOF IN COSMETIC FORMULATIONS BASF AKTIENGESELLSCHAFT (DE) 2003-10-02 WO claimed
WO-2003013748-A1 ACHIEVING A LOTUS EFFECT BY PREVENTING MICROBIAL GROWTH AFTER DAMAGE TO THE SELF-CLEANING SURFACE CREAVIS GESELLSCHAFT FÜR TECHNOLOGIE UND INNOVATION MBH (DE) 2003-02-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050084469-A1 Cationic polymers and the use thereof in cosmetic formulations PARN, CUTA, PARG KDM4E 2369/4885MAPK1 3992/4885HIF1A 3610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.