Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 3/20 | 0.46 |
| ▸ | NSD2 | O96028 | 2/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28987914 | 0.86 | PRMT1 (0.59) | PRMT1ALDH1A1KDM4ENPC1CASP6 | |
| SCHEMBL28709255 | 0.81 | PRMT1 (0.53) | PRMT1CASP6NSD2DUSP3PTPN5 | |
| SCHEMBL28708886 | 0.79 | PRMT1 (0.56) | PRMT1ALDH1A1KDM4ENPC1HPGD | |
| SCHEMBL28691759 | 0.79 | PRMT1 (0.56) | PRMT1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9215027 | 0.77 | NSD2 (0.68) | PRMT1KDM4ENPC1CASP6NSD2 | |
| SCHEMBL28685686 | 0.76 | CA1 (0.55) | PRMT1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7625817 | 0.75 | PRMT1 (0.65) | PRMT1ALDH1A1HSD17B10CASP6NSD2 | |
| SCHEMBL1373255 | 0.75 | PRMT1 (0.65) | PRMT1ALDH1A1HSD17B10CASP6NSD2 | |
| SCHEMBL28933627 | 0.74 | PRMT1 (0.54) | PRMT1MAPTHPGDCASP6NSD2 | |
| SCHEMBL28701649 | 0.74 | PRMT1 (0.57) | PRMT1ALDH1A1RAB9ASMN1; SMN2CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473498-A | Water-soluble, fiber-reactive organic dyestuffs containing a β-chloro-ethylsulfonyl-methyl-benzoic acid amide group | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |