SCHEMBL28709255

SCHEMBL28709255

O=S(=O)(O)c1cc(O)c2ccc(NCc3cccc(Br)c3)cc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 2/20 0.53
CASP6 P55212 3/20 0.47
NSD2 O96028 2/20 0.47
DUSP3 P51452 2/20 0.47
PTPN5 P54829 2/20 0.47
PTPN11 Q06124 2/20 0.47
FFAR1 O14842 1/20 0.46
FFAR4 Q5NUL3 1/20 0.46
CTDSP1 Q9GZU7 1/20 0.46
CASP7 P55210 1/20 0.44
NT5E P21589 2/20 0.42
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
ALOX12 P18054 3/20 0.40
SIRT1 Q96EB6 1/20 0.40
INSR P06213 1/20 0.40
IGF1R P08069 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28987914 0.87 PRMT1 (0.59) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL11222945 0.82 FFAR1 (0.51) FFAR1FFAR4
SCHEMBL29240859 0.82 CASP6 (0.62) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL11228429 0.81 FFAR1 (0.59) FFAR1FFAR4CA12CA1CA2
SCHEMBL11048362 0.81 PRMT1 (0.52) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL28691759 0.80 PRMT1 (0.56) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL28708886 0.80 PRMT1 (0.56) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL9215027 0.78 NSD2 (0.68) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL28685686 0.77 CA1 (0.55) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL1373255 0.76 PRMT1 (0.65) PRMT1CASP6NSD2DUSP3PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114008143-A Azo compound, polarizing film containing the same, and polarizing plate 日本化药株式会社 2022-02-01 CN disclosed