SCHEMBL1373255

SCHEMBL1373255

O=S(=O)(O)CNc1ccc2c(O)cc(S(=O)(=O)O)cc2c1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 2/20 0.65
CASP6 P55212 4/20 0.57
NSD2 O96028 3/20 0.57
DUSP3 P51452 2/20 0.57
PTPN5 P54829 2/20 0.57
PTPN11 Q06124 2/20 0.57
CTDSP1 Q9GZU7 1/20 0.54
NT5E P21589 3/20 0.50
CASP7 P55210 1/20 0.50
SIRT1 Q96EB6 1/20 0.48
SNCA P37840 2/20 0.40
ALDH1A1 P00352 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HSD17B10 Q99714 1/20 0.39
APEX1 P27695 1/20 0.36
EGFR P00533 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4436179 0.90 CASP6 (0.63) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL14645645 0.86 PRMT1 (0.62) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL7625817 0.85 PRMT1 (0.65) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL10648651 0.84 PRMT1 (0.63) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL8947660 0.83 PRMT1 (0.62) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL11219394 0.83 PRMT1 (0.66) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL4650504 0.83 SNCA (0.57) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL30213847 0.83 PRMT1 (0.74) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL9236771 0.83 PRMT1 (0.74) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL9338716 0.81 PRMT1 (0.59) PRMT1CASP6NSD2DUSP3PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2694473-B1 FIBRE-REACTIVE DYES, THEIR PREPARATION AND THEIR USE HUNTSMAN ADV MAT SWITZERLAND (CH) 2019-01-02 EP disclosed
EP-2391683-B1 FIBER-REACTIVE COPPER COMPLEX DISAZO DYES DYSTAR COLOURS DISTRIB GMBH (DE) 2017-03-29 EP disclosed
CN-103443073-B Fibre-reactive dyes, their preparation and their use 亨斯迈先进材料(瑞士)有限公司 2016-09-28 CN disclosed
US-9062208-B2 Fiber-reactive copper complex disazo dyes DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2015-06-23 US disclosed
EP-2694473-A1 FIBRE-REACTIVE DYES, THEIR PREPARATION AND THEIR USE Huntsman Advanced Materials (Switzerland) GmbH (CH) 2014-02-12 EP disclosed
US-20140026333-A1 Fibre-Reactive Dyes, Their Preparation and Their Use HUNTSMAN INTERNATIONAL LLC 2014-01-30 US disclosed
WO-2012136428-A1 FIBRE-REACTIVE DYES, THEIR PREPARATION AND THEIR USE HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2012-10-11 WO disclosed
US-20110283465-A1 FIBER-REACTIVE COPPER COMPLEX DISAZO DYES DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2011-11-24 US disclosed
WO-2010086243-A2 FIBER-REACTIVE COPPER COMPLEX DISAZO DYES DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2010-08-05 WO disclosed
US-7708786-B2 Dye mixtures of fiber-reactive azo dyes, their preparation and use DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2010-05-04 US disclosed
EP-1930379-A2 Reactive red dye composition and application thereof Everlight USA, Inc. (US) 2008-06-11 EP disclosed
CN-101195715-A Reactive orchil component and uses thereof ETHICAL INTERNAT TRADING & WAR (CN) 2008-06-11 CN disclosed
US-20080127433-A1 Reactive red dye composition and application thereof EVERLIGHT USA, INC. (US) 2008-06-05 US disclosed
US-20070271711-A1 Dye Mixtures of Fibre-Reactive Azo Dyes Production and Use Thereof DYSTAR TEXTILFARBEN GMBH & CO., DEUTSCHLAND KG (DE) 2007-11-29 US disclosed
US-7132515-B2 Fiber-reactive AZO dyes, preparation thereof and use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2006-11-07 US disclosed
US-20050166339-A1 Dye mixtures of fiber-reactive azo dyes, their preparation and use DYSTAR TEXTILFARBEN GMBH & CO.DEUTSCHLAND KG (DE) 2005-08-04 US disclosed
US-20050150063-A1 Fiber-reactive azo dyes, preparation thereof and use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-07-14 US disclosed
US-20050034252-A1 Dye mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO. (DE) 2005-02-17 US disclosed
US-20050034253-A1 Mixture; ink for ink jet printing DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-02-17 US disclosed
US-4144231-A Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component CASSELLA AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050034252-A1 Dye mixtures of fiber-reactive azo dyes, their preparation and their use CRY1, FZD7, CBR3 PRMT1 458/4885CASP6 2589/4885NSD2 628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.