Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048409 | 1.00 | LMNA (0.40) | LMNACYP1A2CYP2D6TSHRBLM | |
| SCHEMBL10883239 | 0.76 | FBP1 (0.45) | LMNACYP1A2KMT2AMEN1ALDH1A1 | |
| SCHEMBL11204468 | 0.76 | FBP1 (0.45) | LMNACYP1A2KMT2AMEN1ALDH1A1 | |
| SCHEMBL11041662 | 0.76 | FBP1 (0.45) | LMNACYP1A2KMT2AMEN1ALDH1A1 | |
| SCHEMBL11048410 | 0.74 | NR1I2 (0.42) | LMNACYP1A2CYP2D6TSHRBLM | |
| SCHEMBL11044689 | 0.74 | CYP2C9 (0.44) | NPSR1ALDH1A1GLAMAOANR1I2 | |
| SCHEMBL11044687 | 0.74 | CYP2C9 (0.44) | NPSR1ALDH1A1GLAMAOANR1I2 | |
| SCHEMBL11043470 | 0.71 | MAPT (0.47) | LMNACYP1A2NPSR1KMT2AALDH1A1 | |
| SCHEMBL10883711 | 0.71 | MAPT (0.47) | LMNACYP1A2NPSR1KMT2AALDH1A1 | |
| SCHEMBL10950878 | 0.71 | PAX8 (0.33) | TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473560-A | Diphosphonic acid derivatives and pharmaceutical preparations containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |