SCHEMBL1104849

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2474113	1.00	TRPM4 (0.44)	TRPM4CYP11B1ALDH1A1HSD17B10HPGD
	SCHEMBL28423156	0.87	CYP1A2 (0.45)	TRPM4CYP11B1ALDH1A1HSD17B10HPGD
	SCHEMBL368234	0.84	TRPM4 (0.54)	TRPM4CYP11B1ALDH1A1HSD17B10HPGD
	SCHEMBL17371017	0.84	MAPT (0.45)	ALDH1A1MAPK1MAPTCYP1A2KDM4E
	SCHEMBL21102242	0.83	ALDH1A1 (0.46)	TRPM4CYP11B1ALDH1A1HSD17B10HPGD
	SCHEMBL29952492	0.81	AKR1C3 (0.41)	ALDH1A1HSD17B10HPGDTSHRMAPT
	SCHEMBL26813563	0.81	AKR1C3 (0.41)	ALDH1A1HSD17B10HPGDTSHRMAPT
	SCHEMBL2474387	0.78	CYP11B1 (0.50)	TRPM4CYP11B1ALDH1A1HSD17B10HPGD
	SCHEMBL1427222	0.77	MAPT (0.50)	ALDH1A1MAPK1MAPTCYP1A2KDM4E
	SCHEMBL29875461	0.77	MAPT (0.50)	ALDH1A1MAPK1MAPTCYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.