SCHEMBL17371017

SCHEMBL17371017

OB(O)c1ccc(-c2ccc(B(O)O)c3ccccc23)c2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.45
ENPP2 Q13822 2/20 0.39
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
LIPE Q05469 1/20 0.36
ORAI1 Q96D31 2/20 0.33
ORAI2 Q96SN7 2/20 0.33
ORAI3 Q9BRQ5 2/20 0.33
IDO1 P14902 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
CYP1A2 P05177 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MGLL Q99685 1/20 0.32
PCSK9 Q8NBP7 1/20 0.32
TRPV6 Q9H1D0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1427222 0.92 MAPT (0.50) MAPTENPP2CA4CA6CA5A
SCHEMBL29875461 0.92 MAPT (0.50) MAPTENPP2CA4CA6CA5A
SCHEMBL17367526 0.91 MAPT (0.39) MAPTENPP2CA4CA6CA5A
SCHEMBL28995935 0.87 PKM (0.41) MAPTENPP2LIPECYP1A2KDM4E
SCHEMBL29952492 0.87 AKR1C3 (0.41) MAPTCYP1A2CA1CA2KDM4E
SCHEMBL26813563 0.87 AKR1C3 (0.41) MAPTCYP1A2CA1CA2KDM4E
SCHEMBL29634457 0.86 RAB9A (0.42) MAPTENPP2CA4CA6CA5A
SCHEMBL2163458 0.86 RAB9A (0.42) MAPTENPP2CA4CA6CA5A
SCHEMBL28464197 0.85 CRHBP (0.38) MAPTENPP2LIPECYP1A2KDM4E
SCHEMBL28583021 0.85 MAPT (0.36) MAPTENPP2LIPE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150380655-A1 ANTHRACENE DERIVATIVE, METHOD FOR PREPARING THE SAME, USE THEREOF AND ORGANIC LIGHT EMITTING DEVICE BOE TECHNOLOGY GROUP CO., LTD. (CN) 2015-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150380655-A1 ANTHRACENE DERIVATIVE, METHOD FOR PREPARING THE SAME, USE THEREOF AND ORGANIC LIGHT EMITTING DEVICE ALAD, PPOX, CYBA MAPT 2531/4885ENPP2 920/4885CA4 2344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.