SCHEMBL1104852

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30425546	0.80	CA1 (0.50)	DHODHADORA2AADORA2BCA1CA2
	SCHEMBL1104846	0.79	ESR1 (0.49)	DHODHRAB9ANPC1MEN1KMT2A
	SCHEMBL10175105	0.78	DHODH (0.41)	DHODHRAB9ANPC1MEN1KMT2A
	SCHEMBL28850235	0.78	DHODH (0.44)	DHODHRAB9ANPC1MEN1KMT2A
	SCHEMBL16806054	0.77	NPC1 (0.50)	DHODHRAB9ANPC1MEN1KMT2A
	SCHEMBL505544	0.77	DHODH (1.00)	DHODHRAB9ANPC1ADORA2AADORA2B
	SCHEMBL822550	0.76	DHODH (0.51)	DHODHRAB9ANPC1MEN1KMT2A
	SCHEMBL517706	0.76	MEN1 (0.77)	RAB9ANPC1MEN1KMT2AATM
	SCHEMBL12354486	0.75	MDM2 (0.57)	DHODHMEN1KMT2AATMALDH1A1
	SCHEMBL22502906	0.74	NPC1 (0.47)	DHODHRAB9ANPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.