Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10780696 | 0.83 | — | — | |
| SCHEMBL7280628 | 0.79 | ALDH1A1 (0.39) | ALDH1A1LMNATHRBRECQLTSHR | |
| SCHEMBL10408615 | 0.77 | LMNA (0.35) | ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9711862 | 0.76 | LMNA (0.33) | ALDH1A1LMNA | |
| SCHEMBL5523348 | 0.71 | FFAR1 (0.41) | ALDH1A1THRBRECQLTSHRCYP2C19 | |
| SCHEMBL9451010 | 0.70 | ALDH1A1 (0.32) | ALDH1A1THRBRECQLTSHRCYP2C19 | |
| SCHEMBL8370154 | 0.69 | — | — | |
| SCHEMBL9711852 | 0.68 | — | — | |
| SCHEMBL30170231 | 0.68 | — | — | |
| SCHEMBL45523 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440947-A | Preparation of substituted alpha-halogeno-propionic acids and their derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1984-04-03 | — | — | US | claimed |
| US-4440947-A | Preparation of substituted alpha-halogeno-propionic acids and their derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1984-04-03 | — | — | US | disclosed |
| EP-0061629-A2 | Process for the preparation of substituted alpha-halopropionic acids and of their derivatives; substituted vinylidene chloride | BAYER AG (DE) | 1982-10-06 | — | — | EP | disclosed |