Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593084 | 0.75 | ALDH1A1 (0.55) | MT-CO2ALOX5GAALMNAKDM4E | |
| SCHEMBL9636719 | 0.75 | ALDH1A1 (0.55) | MT-CO2ALOX5GAALMNAKDM4E | |
| SCHEMBL7758607 | 0.74 | KDM4E (0.40) | MT-CO2ALOX5KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4567677 | 0.74 | HTT (0.52) | MT-CO2ALOX5GAALMNAKDM4E | |
| SCHEMBL9654949 | 0.74 | GAA (0.50) | MT-CO2ALOX5GAALMNAKDM4E | |
| SCHEMBL3563708 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HPGDPOLB | |
| SCHEMBL5691873 | 0.72 | MT-CO2 (0.56) | MT-CO2ALOX5GAALMNAKDM4E | |
| SCHEMBL8530088 | 0.72 | MT-CO2 (0.55) | MT-CO2ALOX5GAALMNAKDM4E | |
| SCHEMBL3562356 | 0.72 | POLB (0.37) | ALOX5POLB | |
| SCHEMBL8080652 | 0.72 | POLB (0.37) | ALOX5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443436-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1984-04-17 | — | — | US | disclosed |