Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048580 | 0.74 | MT-CO2 (0.57) | KDM4ESMN1; SMN2MT-CO2ALOX5ALDH1A1 | |
| SCHEMBL9636719 | 0.71 | ALDH1A1 (0.55) | KDM4ETSHRSMN1; SMN2KMT2AMT-CO2 | |
| SCHEMBL3593084 | 0.71 | ALDH1A1 (0.55) | KDM4ETSHRSMN1; SMN2KMT2AMT-CO2 | |
| SCHEMBL20503163 | 0.71 | KMT2A (0.41) | TSHRSMN1; SMN2KMT2AALDH1A1PKM | |
| SCHEMBL3563708 | 0.69 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL24223726 | 0.69 | ALDH1A1 (0.49) | TSHRKMT2AALDH1A1 | |
| SCHEMBL8080652 | 0.68 | POLB (0.37) | TSHRKMT2AALOX5 | |
| SCHEMBL3562356 | 0.68 | POLB (0.37) | TSHRKMT2AALOX5 | |
| SCHEMBL7099567 | 0.67 | KMT2A (0.43) | TSHRKMT2AALDH1A1SLC18A3 | |
| SCHEMBL8088848 | 0.66 | POLB (0.36) | TSHRKMT2AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642357-B1 | RADIOLABELLED SOMATOSTATIN | MALLINCKRODT INC (US) | 2001-07-25 | — | — | EP | disclosed |
| EP-1099693-A1 | Radiolabelled peptide compounds | MALLINCKRODT INC. (US) | 2001-05-16 | — | — | EP | disclosed |
| US-5656253-A | Ligands useful in radiographic imaging | MALLINCKRODT MEDICAL, INC. (US) | 1997-08-12 | — | — | US | disclosed |
| EP-0642357-A4 | RADIOLABELLED PEPTIDE COMPOUNDS. | — | 1995-04-05 | — | — | EP | disclosed |
| EP-0642357-A1 | RADIOLABELLED PEPTIDE COMPOUNDS | MALLINCKRODT MEDICAL, INC. (US) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993015770-A1 | RADIOLABELLED PEPTIDE COMPOUNDS | MALLINCKRODT MEDICAL, INC. (US) | 1993-08-19 | — | — | WO | disclosed |