Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049115 | 0.80 | LMNA (0.49) | ALDH1A1LMNAMAPK1CA12CA1 | |
| SCHEMBL12603518 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPK1TSHRCA12 | |
| SCHEMBL23732206 | 0.77 | DAO (0.57) | ALDH1A1LMNAMAPK1CA12CA1 | |
| SCHEMBL11459269 | 0.76 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPK1TSHRCA12 | |
| SCHEMBL3932937 | 0.74 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPK1TSHRHSD17B10 | |
| SCHEMBL287087 | 0.73 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPK1TSHRHSD17B10 | |
| SCHEMBL28297166 | 0.72 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPK1TSHRCA12 | |
| SCHEMBL31487941 | 0.71 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPK1TSHRCA12 | |
| SCHEMBL4547877 | 0.71 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPK1TSHRHSD17B10 | |
| SCHEMBL28297048 | 0.70 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPK1TSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430355-A | ARTIFICIAL SWEETENER | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-02-07 | — | — | US | disclosed |
| US-4233333-A | 4,5-Dimethyl-thieno[3,2-d]isothiazolo-3(2H)-one-1,1-dioxides, compositions, and methods of use as a sweetener | BOEHRINGER INGELHEIM GMBH (DE) | 1980-11-11 | — | — | US | disclosed |