SCHEMBL28297048

SCHEMBL28297048

Cc1cc(C(N)=O)c(S(=O)(=O)Cl)s1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
LMNA P02545 2/20 0.50
MAPK1 P28482 1/20 0.50
MAPT P10636 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
GAA P10253 2/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA13 Q8N1Q1 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
TSHR P16473 1/20 0.34
NNMT P40261 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28297166 0.84 ALDH1A1 (0.51) ALDH1A1LMNAMAPK1MAPTL3MBTL1
Hydrochloric Acid SCHEMBL28297050 0.82 ALDH1A1 (0.50) ALDH1A1LMNAMAPK1MAPTL3MBTL1
SCHEMBL8653214 0.73 DAO (0.41) ALDH1A1LMNAMAPK1MAPTL3MBTL1
SCHEMBL4606362 0.73 ALDH1A1 (0.43) ALDH1A1LMNAMAPK1MAPTTSHR
SCHEMBL22508643 0.72 ALDH1A1 (0.41) ALDH1A1LMNAMAPK1MAPTGAA
SCHEMBL17367390 0.72 PLA2G10 (0.49) ALDH1A1LMNAMAPK1MAPTL3MBTL1
SCHEMBL19494881 0.71 CA12 (0.35) ALDH1A1LMNAMAPK1L3MBTL1GAA
SCHEMBL166884 0.71 ALDH1A1 (0.58) ALDH1A1LMNAMAPK1MAPTL3MBTL1
SCHEMBL11048762 0.70 ALDH1A1 (0.73) ALDH1A1LMNAMAPK1MAPTL3MBTL1
SCHEMBL19436829 0.69 ALDH1A1 (0.40) ALDH1A1LMNAMAPK1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105960400-B Sulfamoylthiophene amide derivatives and its purposes for being used to treat hepatitis B as drug 爱尔兰詹森科学公司 2019-05-31 CN disclosed