Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 5/20 | 0.46 |
| ▸ | ATP4B | P51164 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691485 | 0.82 | POLB (0.39) | MAPK1RAB9AHCRTR1TP53MAPT | |
| SCHEMBL10690155 | 0.81 | ATP4A (0.55) | ATP4AATP4BMAPK1MEN1KMT2A | |
| Iodide SCHEMBL10692950 | 0.81 | HCRTR1 (0.33) | MAPK1RAB9AHCRTR1TP53MAPT | |
| SCHEMBL10694506 | 0.76 | ATP4A (0.48) | ATP4AATP4BMAPK1MEN1KMT2A | |
| SCHEMBL2189930 | 0.69 | ATP4A (0.81) | ATP4AATP4BMAPK1MEN1KMT2A | |
| SCHEMBL5633386 | 0.68 | ATP4A (0.60) | ATP4AATP4BMAPK1MEN1KMT2A | |
| SCHEMBL5633236 | 0.68 | ATP4A (0.60) | ATP4AATP4BMAPK1MEN1KMT2A | |
| SCHEMBL11048807 | 0.65 | CHEK1 (0.55) | ATP4AATP4BMAPK1MEN1KMT2A | |
| SCHEMBL10686609 | 0.65 | ATP4A (0.74) | ATP4AATP4BMAPK1MEN1KMT2A | |
| SCHEMBL10691749 | 0.64 | POLB (0.40) | MEN1KMT2ABLMRAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738967-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| US-4686227-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-08-11 | — | — | US | disclosed |
| EP-0165545-A2 | Imidazoisoquinoline compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-12-27 | — | — | EP | disclosed |