SCHEMBL11048852

SCHEMBL11048852

Cc1cc(S(=O)(=O)Cl)sc1C

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
DAO P14920 1/20 0.39
KMT2A Q03164 1/20 0.39
TSHR P16473 1/20 0.32
TP53 P04637 1/20 0.30
GAA P10253 1/20 0.30
ALOX15 P16050 1/20 0.30
NFKB1 P19838 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28295495 0.83 TSHR (0.36) ALDH1A1KDM4EMEN1KMT2ATSHR
SCHEMBL14503136 0.80 TSHR (0.38) ALDH1A1MAPTTSHRGAASMN1; SMN2
SCHEMBL9997249 0.80 DAO (0.44) DAO
SCHEMBL4534390 0.78 GAA (0.31) MAPTGAA
SCHEMBL31560167 0.77 MAPT (0.39) ALDH1A1MAPTKDM4EMEN1DAO
SCHEMBL9424674 0.77 CA2 (0.42) ALDH1A1MAPTKDM4EMEN1DAO
Hydrochloric Acid SCHEMBL11048859 0.76 MAPT (0.42) ALDH1A1MAPTKDM4EMEN1DAO
SCHEMBL16236942 0.74 ALDH1A1 (0.43) ALDH1A1MAPTKDM4EMEN1DAO
SCHEMBL16237290 0.74 GSK3B (0.36) ALDH1A1
SCHEMBL19494881 0.72 CA12 (0.35) ALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119899170-A Fluorine-containing thiophene compound, preparation method thereof and electrolyte 江苏华盛锂电材料股份有限公司 2025-04-29 CN disclosed
US-4430355-A ARTIFICIAL SWEETENER DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-02-07 US disclosed
US-4233333-A 4,5-Dimethyl-thieno[3,2-d]isothiazolo-3(2H)-one-1,1-dioxides, compositions, and methods of use as a sweetener BOEHRINGER INGELHEIM GMBH (DE) 1980-11-11 US disclosed