Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048852 | 0.80 | ALDH1A1 (0.39) | TSHRALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL392578 | 0.80 | ALDH1A1 (0.52) | TSHRALDH1A1TAAR1MAPTHPGD | |
| SCHEMBL10590843 | 0.78 | CDK1 (0.41) | TSHRALDH1A1TRPV4TAAR1HPGD | |
| SCHEMBL2977321 | 0.77 | ALDH1A1 (0.33) | TSHRALDH1A1TRPV4TAAR1HPGD | |
| SCHEMBL2265194 | 0.76 | PKM (0.35) | TRPV4 | |
| SCHEMBL16237271 | 0.72 | DAO (0.55) | ALDH1A1MAPT | |
| SCHEMBL16237290 | 0.72 | GSK3B (0.36) | ALDH1A1 | |
| SCHEMBL16236942 | 0.72 | ALDH1A1 (0.43) | TSHRALDH1A1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1940760 | 0.71 | PSMB8 (0.40) | TSHRALDH1A1MAPTHPGDGAA | |
| SCHEMBL19494881 | 0.71 | CA12 (0.35) | ALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217738-B2 | β2-adrenergic receptor agonists | THERAVANCE, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-7217738-B2 | β2-adrenergic receptor agonists | THERAVANCE, INC. (US) | 2007-05-15 | — | — | US | disclosed |