Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | SLC8A1 | P32418 | 9/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3488386 | 0.92 | ESR1 (0.56) | ESR1ESR2DRD2DRD3PNMT | |
| SCHEMBL3487847 | 0.89 | ESR1 (0.56) | ESR1ESR2SLC8A1CYP19A1 | |
| SCHEMBL10510220 | 0.76 | DRD2 (0.37) | ESR1ESR2DRD2DRD3PNMT | |
| SCHEMBL19230545 | 0.75 | ESR1 (0.53) | ESR1ESR2CYP19A1 | |
| SCHEMBL7393168 | 0.75 | CA2 (0.38) | ESR1ESR2DRD2DRD3PNMT | |
| SCHEMBL10509432 | 0.75 | DRD2 (0.36) | ESR1ESR2DRD2DRD3PNMT | |
| SCHEMBL4949842 | 0.75 | SLC8A1 (0.51) | SLC8A1 | |
| SCHEMBL15913830 | 0.73 | ESR2 (1.00) | ESR1ESR2CYP19A1 | |
| SCHEMBL4461737 | 0.73 | ESR1 (0.67) | ESR1ESR2SLC8A1 | |
| SCHEMBL27849981 | 0.73 | ESR1 (0.67) | ESR1ESR2SLC8A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461907-A | Amino-substituted flavans useful as anti-viral agents | BURROUGHS WELLCOME CO. | 1984-07-24 | — | — | US | disclosed |