Ethylene Glycol

Ethylene Glycol

SCHEMBL11048976

CCCCN/C(C)=C\C(=O)OCCCCOC(=O)/C=C(/C)NCCCC.OCCO

nearest known ligand 0.54

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Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.54
ATM Q13315 1/20 0.44
HCAR2 Q8TDS4 3/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11048980 0.95 ACHE (0.56) ACHEATMHCAR2HPGDTSHR
SCHEMBL19602219 0.89 ACHE (0.50) ACHEATMHCAR2HPGDTSHR
SCHEMBL17845073 0.89 ACHE (0.50) ACHEATMHCAR2HPGDTSHR
SCHEMBL10665052 0.83 ACHE (0.47) ACHE
SCHEMBL10653785 0.83 ACHE (0.47) ACHE
SCHEMBL11996069 0.82 ACHE (0.47) ACHEATMHPGDTSHR
SCHEMBL10989604 0.81 ZDHHC20 (0.43) ACHEATMHPGDTSHR
SCHEMBL19921740 0.80 ATM (0.55) ACHEATMHCAR2HPGDTSHR
SCHEMBL1143798 0.80 ACHE (0.46) ACHE
SCHEMBL1143801 0.80 ACHE (0.46) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4424336-A Meat-curable mixture, which are stable on storage, of epoxide resin, 3-aminocrotonic acid derivatives and maleimide compound CIBA-GEIGY CORPORATION (US) 1984-01-03 US disclosed
US-4360655-A Heat-curable mixtures, which are stable on storage, of epoxide compounds β-aminocrotonic acid derivatives and polyamine CIBA-GEIGY CORPORATION (US) 1982-11-23 US disclosed
US-4291146-A Heat-curable mixtures, which are stable on storage, of expoxide resins and β-aminocrotonic acid derivatives CIBA-GEIGY CORPORATION (US) 1981-09-22 US disclosed