SCHEMBL11049152

SCHEMBL11049152

Cc1cc(=O)n(-c2ccc(I)cc2)n1C

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 2/20 0.68
FAAH O00519 1/20 0.38
MGLL Q99685 1/20 0.38
BCHE P06276 3/20 0.38
FPR2 P25090 1/20 0.36
APP P05067 1/20 0.33
CASP3 P42574 1/20 0.33
ALOX15 P16050 2/20 0.32
PTGS2 P35354 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 2/20 0.31
ADORA3 P0DMS8 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP1A2 P05177 1/20 0.30
THRB P10828 1/20 0.30
TSHR P16473 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5052007 0.85 NAPRT (0.72) NAPRTMGLLALDH1A1LMNAPOLB
SCHEMBL4322796 0.81 NAPRT (0.68) NAPRTMGLLALOX15ALDH1A1LMNA
SCHEMBL11005335 0.81 NAPRT (0.68) NAPRTFAAHMGLLBCHEFPR2
SCHEMBL3531406 0.81 NAPRT (0.68) NAPRTMGLLFPR2POLBKMT2A
SCHEMBL4849110 0.81 NAPRT (0.68) NAPRTBCHEPTGS2ALDH1A1LMNA
Antipyrine SCHEMBL20452 0.81 NAPRT (1.00) NAPRTBCHEALOX15PTGS2ALDH1A1
Antipyrine SCHEMBL8736656 0.79 NAPRT (0.96) NAPRTBCHEALOX15PTGS2ALDH1A1
Antipyrine SCHEMBL8995343 0.79 NAPRT (0.96) NAPRTBCHEALOX15PTGS2ALDH1A1
Antipyrine SCHEMBL18260589 0.79 NAPRT (0.96) NAPRTBCHEALOX15PTGS2ALDH1A1
Antipyrine SCHEMBL28445203 0.79 NAPRT (0.96) NAPRTBCHEALOX15PTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118026938-B Pyrazolone ester compound and electrochemical synthesis method thereof 江西本草天工科技有限责任公司 2024-06-28 CN claimed
CN-118026938-A Pyrazolone ester compound and electrochemical synthesis method thereof 江西本草天工科技有限责任公司 2024-05-14 CN claimed
US-4268626-A Dry image forming material ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1981-05-19 US claimed
CN-118026938-B Pyrazolone ester compound and electrochemical synthesis method thereof 江西本草天工科技有限责任公司 2024-06-28 CN disclosed
CN-118026938-A Pyrazolone ester compound and electrochemical synthesis method thereof 江西本草天工科技有限责任公司 2024-05-14 CN disclosed
US-4442202-A SILVER HALIDE, REDOX SYSTEM, ORGANOBROMINE COMPOUND, STORAGE STABILITY ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-04-10 US disclosed
US-4396712-A ORGANIC SILVER SALT OXIDIZER, REDUCING AGENT, SILVER HALIDE OR SILVER HALIDE FORMER, TONER, BINDER, HYDROXYPHENYLBENZOTRIAZOLE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1983-08-02 US disclosed
US-4332889-A IMPROVED SENSITIVITY, STORAGE STABILITY ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-06-01 US disclosed
US-4268626-A Dry image forming material ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1981-05-19 US disclosed