Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 18/20 | 0.51 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769809 | 0.78 | CD274 (0.42) | CD274PDCD1 | |
| SCHEMBL21620376 | 0.77 | CD274 (0.53) | CD274PDCD1EPHX1 | |
| SCHEMBL11049259 | 0.76 | CD274 (0.57) | CD274PDCD1EPHX1 | |
| SCHEMBL23367902 | 0.75 | CD274 (0.47) | CD274PDCD1EPHX1 | |
| SCHEMBL8769172 | 0.75 | IDO1 (0.43) | — | |
| SCHEMBL11056588 | 0.74 | CD274 (0.46) | CD274PDCD1 | |
| SCHEMBL11056547 | 0.74 | CD274 (0.46) | CD274PDCD1 | |
| SCHEMBL11057216 | 0.74 | CD274 (0.40) | CD274PDCD1EPHX1 | |
| SCHEMBL11057211 | 0.74 | CD274 (0.40) | CD274PDCD1EPHX1 | |
| SCHEMBL8769631 | 0.74 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792870-A1 | Process for the preparation of ketoximethers by coupling with boronic acid derivatives | Hoechst Schering AgrEvo GmbH (DE) | 1997-09-03 | — | — | EP | disclosed |