Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22465826 | 0.78 | LIPG (0.33) | ALDH1A1HPGD | |
| SCHEMBL11049449 | 0.74 | LMNA (0.42) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL11050586 | 0.67 | TDP1 (0.43) | NPC1ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL3468425 | 0.64 | TDP1 (0.46) | NPC1ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL13826361 | 0.63 | CA1 (0.46) | ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11049903 | 0.62 | TDP1 (0.43) | NPC1ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1299653 | 0.62 | MAPT (0.38) | NPC1ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL2864849 | 0.62 | LMNA (0.46) | ALDH1A1HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27758706 | 0.61 | MAPT (0.37) | NPC1ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL11115011 | 0.61 | GAA (0.36) | NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430355-A | ARTIFICIAL SWEETENER | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-02-07 | — | — | US | disclosed |
| US-4233333-A | 4,5-Dimethyl-thieno[3,2-d]isothiazolo-3(2H)-one-1,1-dioxides, compositions, and methods of use as a sweetener | BOEHRINGER INGELHEIM GMBH (DE) | 1980-11-11 | — | — | US | disclosed |