SCHEMBL11049482

SCHEMBL11049482

O=S(OCCBr)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP24A1 Q07973 1/20 0.37
TDP1 Q9NUW8 2/20 0.33
ALDH1A1 P00352 2/20 0.33
EPHX2 P34913 1/20 0.32
TRPA1 O75762 1/20 0.31
TSHR P16473 1/20 0.31
PTPN1 P18031 1/20 0.30
GSK3B P49841 1/20 0.30
RECQL P46063 1/20 0.30
LOX P28300 1/20 0.30
NPC1 O15118 1/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1847372 0.79 CYP24A1 (0.37) CYP24A1TDP1ALDH1A1EPHX2RECQL
SCHEMBL27804754 0.79 ALDH1A1 (0.43) CYP24A1TDP1ALDH1A1EPHX2PTPN1
SCHEMBL11286528 0.79 LMNA (0.46) CYP24A1TDP1ALDH1A1EPHX2TSHR
SCHEMBL28316278 0.78 LMNA (0.44) CYP24A1TDP1ALDH1A1EPHX2TSHR
SCHEMBL1846993 0.76 CYP24A1 (0.41) CYP24A1TDP1EPHX2LOXMAPT
SCHEMBL6002555 0.76 TSHR (0.46) CYP24A1TDP1ALDH1A1EPHX2TSHR
SCHEMBL1847989 0.75 CYP24A1 (0.40) CYP24A1TDP1LOXSMN1; SMN2
SCHEMBL6002444 0.75 TSHR (0.47) CYP24A1TDP1ALDH1A1EPHX2TSHR
SCHEMBL3088326 0.74 EPHX1 (0.37) CYP24A1TDP1ALDH1A1EPHX2TSHR
SCHEMBL25149290 0.74 TSHR (0.39) CYP24A1TDP1ALDH1A1EPHX2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4444926-A Method of hardening gelatin and photographic materials produced thereby FUJI PHOTO FILM CO., LTD. (JP) 1984-04-24 US disclosed