Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049580 | 0.90 | LMNA (0.61) | LMNACYP3A4ACHEMTNR1BMTNR1A | |
| SCHEMBL5040450 | 0.86 | CYP3A4 (0.61) | LMNACYP3A4ACHEMTNR1BMTNR1A | |
| SCHEMBL13250810 | 0.83 | SRD5A2 (0.58) | PPARGPPARAMEN1KMT2AKMO | |
| SCHEMBL14191218 | 0.83 | SRD5A2 (0.58) | PPARGPPARAMEN1KMT2AKMO | |
| SCHEMBL14191212 | 0.83 | SRD5A2 (0.58) | PPARGPPARAMEN1KMT2AKMO | |
| SCHEMBL13252903 | 0.83 | HPGD (0.58) | LMNAMTNR1BMTNR1APPARGPPARA | |
| SCHEMBL2707543 | 0.82 | SRD5A2 (0.62) | LMNACYP3A4GAAKMOKDM4E | |
| SCHEMBL249305 | 0.82 | LMNA (0.76) | LMNACYP3A4ACHEMEN1KMT2A | |
| SCHEMBL17028900 | 0.82 | LMNA (0.76) | LMNACYP3A4ACHEMEN1KMT2A | |
| SCHEMBL16890736 | 0.82 | ALDH1A1 (0.60) | LMNAPPARGPPARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985779-A | ANTIINFLAMMATORY AND ANALGESIC ACTIVITIES | EISAI CO., LTD. (JA) | 1976-10-12 | — | — | US | disclosed |