Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690053 | 0.82 | MEN1 (0.48) | MEN1KMT2ALMNAMAPTADORA1 | |
| SCHEMBL4579407 | 0.82 | KMT2A (0.56) | MEN1KMT2ALMNAMAPTADORA1 | |
| Hydrochloric Acid SCHEMBL9538926 | 0.81 | MEN1 (0.55) | MEN1KMT2ALMNAMAPTADORA1 | |
| SCHEMBL4083554 | 0.78 | LMNA (0.60) | MEN1KMT2ALMNACYP3A4CYP2D6 | |
| SCHEMBL9643788 | 0.78 | LMNA (0.60) | MEN1KMT2ALMNACYP3A4CYP2D6 | |
| SCHEMBL9020807 | 0.78 | MEN1 (0.52) | MEN1KMT2ALMNAMAPTADORA1 | |
| SCHEMBL31397280 | 0.78 | MEN1 (0.52) | MEN1KMT2ALMNAMAPTADORA1 | |
| SCHEMBL9020812 | 0.78 | MEN1 (0.52) | MEN1KMT2ALMNAMAPTADORA1 | |
| SCHEMBL8380136 | 0.77 | SIGMAR1 (0.57) | MEN1KMT2ALMNACYP3A4SIGMAR1 | |
| SCHEMBL2831250 | 0.77 | MEN1 (0.54) | MEN1KMT2ALMNAMAPTADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135318-A1 | Quinazoline cardiac stimulants | Pfizer Limited (GB) | 1985-03-27 | — | — | EP | disclosed |