Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9538926 | 0.99 | MEN1 (0.55) | KMT2AMEN1LMNAMAPTADORA1 | |
| SCHEMBL31397280 | 0.95 | MEN1 (0.52) | KMT2AMEN1LMNAMAPTADORA1 | |
| SCHEMBL2831248 | 0.92 | MEN1 (0.54) | KMT2AMEN1LMNAMAPTADORA1 | |
| SCHEMBL8576896 | 0.92 | MEN1 (0.54) | KMT2AMEN1LMNAMAPTADORA1 | |
| SCHEMBL2831250 | 0.92 | MEN1 (0.54) | KMT2AMEN1LMNAMAPTADORA1 | |
| SCHEMBL6952558 | 0.87 | MAPK1 (0.47) | ALDH1A1MAPK1ESR2SMN1; SMN2 | |
| SCHEMBL14342045 | 0.87 | POLB (0.52) | KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL5036890 | 0.86 | KMT2A (0.48) | KMT2AMEN1LMNACYP3A4CYP2D6 | |
| SCHEMBL8542921 | 0.85 | MEN1 (0.47) | KMT2AMEN1LMNAMAPTADORA1 | |
| SCHEMBL8542919 | 0.85 | MEN1 (0.47) | KMT2AMEN1LMNAMAPTADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868030-A | Preparation method of 1- (1-tert-butyloxycarbonyl-4-piperidylacetyl) -4-methylsulfonyloxypiperidine and 1- (1-tert-butyloxycarbonyl-4-piperidylacetyl) -4-methylsulfonyloxypiperidine | 有机合成药品工业株式会社 | 2020-10-30 | — | — | CN | claimed |
| US-20250340560-A1 | SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS BRUTON'S TYROSINE KINASE MODULATORS | BEIGENE SWITZERLAND GMBH (CH) | 2025-11-06 | — | — | US | disclosed |
| US-20250034170-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2025-01-30 | — | — | US | disclosed |
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| US-20240254128-A1 | SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS BRUTON'S TYROSINE KINASE MODULATORS | BEIGENE SWITZERLAND GMBH (CH) | 2024-08-01 | — | — | US | disclosed |
| CN-111868030-B | 1- (1-Tert-butoxycarbonyl-4-piperidylacetyl) -4-methanesulfonyloxy piperidine and preparation method thereof | 有机合成药品工业株式会社 | 2024-07-19 | — | — | CN | disclosed |
| US-11827603-B2 | Method for preparing 1-(1-tert-butoxycarbonyl-4-piperidylacetyl)-4-mesyloxypiperidine and 1-(1-tert-butoxycarbonyl-4-piperidylacetyl)-4-mesyloxypiperidine | YUKI GOSEI KOGYO CO., LTD. (JP) | 2023-11-28 | — | — | US | disclosed |
| US-11827603-B2 | Method for preparing 1-(1-tert-butoxycarbonyl-4-piperidylacetyl)-4-mesyloxypiperidine and 1-(1-tert-butoxycarbonyl-4-piperidylacetyl)-4-mesyloxypiperidine | YUKI GOSEI KOGYO CO., LTD. (JP) | 2023-11-28 | — | — | US | disclosed |
| US-11827603-B2 | Method for preparing 1-(1-tert-butoxycarbonyl-4-piperidylacetyl)-4-mesyloxypiperidine and 1-(1-tert-butoxycarbonyl-4-piperidylacetyl)-4-mesyloxypiperidine | YUKI GOSEI KOGYO CO., LTD. (JP) | 2023-11-28 | — | — | US | disclosed |
| CN-111868031-B | Process for the preparation of N-alkoxycarbonylpiperidine derivatives and intermediates therefor | 有机合成药品工业株式会社 | 2023-10-03 | — | — | CN | disclosed |
| US-20040063953-A1 | Method of producing N-alkoxycarbonylpiperidine derivative, new compound as raw material therefor, and method of producing the compound | YUKI GOSEI KOGYO CO., LTD. (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1400511-A1 | Methods of producing n-alkoxycarbonylpiperidine derivatives and intermediates therefor | YUKI GOSEI KOGYO CO., LTD. (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-20020119968-A1 | Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents | ZENECA LIMITED | 2002-08-29 | — | — | US | disclosed |
| US-6225309-B1 | Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents | ZENECA LIMITED (GB) | 2001-05-01 | — | — | US | disclosed |
| US-5965559-A | STRONG INHIBITORY EFFECT AGAINST THE ACTIVATED COAGULATION PROTEASE KNOWN AS FACTOR XA; PREVENTION OF THE CLEAVAGE OF PROTHROMBIN TO THROMBIN; AMINO-SUBSTITUTED PYRIMIDINES AMIDINE GROUP-FREE | ZENECA LIMITED (GB) | 1999-10-12 | — | — | US | disclosed |
| EP-0783500-B1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| EP-0783500-A1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LIMITED (GB) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010022-A1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LIMITED (GB) | 1996-04-04 | — | — | WO | disclosed |
| US-4983614-A | ANTISPASMODIC, ANTIALLERGENIC AND ANTIHISTAMINE AGENTS | LES LABORATOIRES MERAM (FR) | 1991-01-08 | — | — | US | disclosed |
| US-4289772-A | PHOSPHODIESTERASE INHIBITORS | PFIZER INC. (US) | 1981-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034170-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | GBA1, GAA, GBA2 | KMT2A 3498/4885MEN1 4454/4885LMNA 2875/4885 |
| US-20240254128-A1 | SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS BRUTON'S TYROSINE KINASE MODULATORS | BTK, LCK, SYK | KMT2A 2628/4885MEN1 3923/4885LMNA 4691/4885 |
| US-11827603-B2 | Method for preparing 1-(1-tert-butoxycarbonyl-4-piperidylacetyl)-4-mesyloxypiperidine and 1-(1-tert-butoxycarbonyl-4-piperidylacetyl)-4-mesyloxypiperidine | AP2A1, TERT, APEH | KMT2A 739/4885MEN1 2255/4885LMNA 2486/4885 |
| US-20020119968-A1 | Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents | SERPINC1, F2, SULT1E1 | KMT2A 1699/4885MEN1 362/4885LMNA 412/4885 |
| US-20040063953-A1 | Method of producing N-alkoxycarbonylpiperidine derivative, new compound as raw material therefor, and method of producing the compound | ORMDL3, MRPS18A, ACSL3 | KMT2A 1972/4885MEN1 187/4885LMNA 3218/4885 |
| US-20250340560-A1 | SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS BRUTON'S TYROSINE KINASE MODULATORS | BTK, LCK, SYK | KMT2A 2628/4885MEN1 3923/4885LMNA 4691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.