Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.32 |
| ▸ | APEX1 | P27695 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28530962 | 0.87 | TDP1 (0.41) | TDP1ALDH1A1HSD17B10TRPV4APEX1 | |
| SCHEMBL31519761 | 0.87 | TDP1 (0.41) | TDP1ALDH1A1HSD17B10TRPV4APEX1 | |
| SCHEMBL2196286 | 0.81 | ALDH1A1 (0.40) | TDP1ALDH1A1HSD17B10TRPV4LMNA | |
| SCHEMBL306373 | 0.78 | ALDH1A1 (0.37) | TDP1ALDH1A1HSD17B10TRPV4CA1 | |
| SCHEMBL29376991 | 0.78 | ALDH1A1 (0.37) | TDP1ALDH1A1HSD17B10TRPV4CA1 | |
| SCHEMBL6516449 | 0.77 | TDP1 (0.39) | TDP1ALDH1A1HSD17B10TRPV4APEX1 | |
| SCHEMBL4517194 | 0.77 | CA1 (0.46) | TDP1ALDH1A1HSD17B10CA1CA2 | |
| SCHEMBL218559 | 0.76 | ALDH1A1 (0.53) | TDP1ALDH1A1HSD17B10TRPV4CA1 | |
| SCHEMBL6520791 | 0.75 | ALDH1A1 (0.37) | TDP1ALDH1A1HSD17B10TRPV4 | |
| SCHEMBL6512667 | 0.75 | ALDH1A1 (0.37) | TDP1ALDH1A1HSD17B10TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061013-B1 | PROCESS FOR THE PREPARATION OF POLYISOCYANATES | BAYER AG (DE) | 1984-06-27 | — | — | EP | disclosed |
| US-4388246-A | THERMAL SPLITTING OF CARBAMATES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-06-14 | — | — | US | disclosed |
| US-4369191-A | COMPLEMENT INHIBITION | AMERICAN CYANAMID COMPANY (US) | 1983-01-18 | — | — | US | disclosed |
| EP-0061013-A1 | Process for the preparation of polyisocyanates | BAYER AG (DE) | 1982-09-29 | — | — | EP | disclosed |
| US-4265830-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
| US-4266077-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1981-05-05 | — | — | US | disclosed |