Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.30 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.30 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306373 | 0.86 | ALDH1A1 (0.37) | ALDH1A1HSD17B10CYP2C9CYP2C19CASP6 | |
| SCHEMBL29376991 | 0.86 | ALDH1A1 (0.37) | ALDH1A1HSD17B10CYP2C9CYP2C19CASP6 | |
| SCHEMBL29044877 | 0.84 | NT5E (0.49) | ALDH1A1HSD17B10CYP2C9CYP2C19CASP6 | |
| SCHEMBL4511235 | 0.84 | PTGES (0.50) | ALDH1A1HSD17B10CYP2C9CYP2C19CASP6 | |
| SCHEMBL11136985 | 0.83 | HTR6 (0.41) | ALDH1A1HSD17B10TDP1LMNAL3MBTL1 | |
| SCHEMBL11049698 | 0.81 | TDP1 (0.40) | ALDH1A1HSD17B10CYP2C9CYP2C19TDP1 | |
| SCHEMBL4517194 | 0.81 | CA1 (0.46) | ALDH1A1HSD17B10CYP2C9CYP2C19TDP1 | |
| SCHEMBL4503836 | 0.80 | MEN1 (0.42) | HSD17B10TDP1LMNAL3MBTL1TRPV4 | |
| SCHEMBL9418644 | 0.79 | HTR6 (0.41) | ALDH1A1HSD17B10CYP2C9CYP2C19CASP6 | |
| SCHEMBL2263563 | 0.79 | LMNA (0.48) | ALDH1A1HSD17B10CYP2C9CYP2C19CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070039874-A1 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY | 2007-02-22 | — | — | US | claimed |
| CN-104010717-A | Membrane, Water Treatment System, And Method Of Making | GEN ELECTRIC | 2014-08-27 | — | — | CN | disclosed |
| CN-103124590-A | Thin film composite membranes incorporating carbon nanotubes | GEN ELECTRIC | 2013-05-29 | — | — | CN | disclosed |
| US-20110168631-A1 | METHODS AND APPARATUSES FOR WATER FILTRATION USING POLYARYLETHER MEMBRANES | GENERAL ELECTRIC COMPANY (US) | 2011-07-14 | — | — | US | disclosed |
| US-7727434-B2 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070039874-A1 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY | 2007-02-22 | — | — | US | disclosed |