SCHEMBL28530962

SCHEMBL28530962

O=S(=O)(Cl)c1cc(S(=O)(=O)Cl)c2cccc(S(=O)(=O)Cl)c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
HSD17B10 Q99714 2/20 0.41
ALDH1A1 P00352 1/20 0.41
CDK2 P24941 1/20 0.37
ALPL P05186 1/20 0.37
ALPI P09923 1/20 0.37
ALPG P10696 1/20 0.37
DNMT1 P26358 1/20 0.37
MCL1 Q07820 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TTR P02766 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CA2 P00918 3/20 0.34
CA1 P00915 2/20 0.34
CA9 Q16790 1/20 0.34
APEX1 P27695 2/20 0.34
CYP3A4 P08684 3/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C9 P11712 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31519761 1.00 TDP1 (0.41) TDP1HSD17B10ALDH1A1CDK2ALPL
SCHEMBL11049698 0.87 TDP1 (0.40) TDP1HSD17B10ALDH1A1L3MBTL1CA2
SCHEMBL29904571 0.85 CDK2 (0.46) TDP1HSD17B10ALDH1A1CDK2ALPL
SCHEMBL3133065 0.85 CDK2 (0.46) TDP1HSD17B10ALDH1A1CDK2ALPL
SCHEMBL11048086 0.85 HSD17B10 (0.39) TDP1HSD17B10ALDH1A1SMN1; SMN2APEX1
SCHEMBL30522380 0.81 TTR (0.42) TDP1HSD17B10CDK2ALPLALPI
SCHEMBL29044876 0.81 TTR (0.42) TDP1HSD17B10CDK2ALPLALPI
SCHEMBL4517194 0.78 CA1 (0.46) TDP1HSD17B10ALDH1A1L3MBTL1CA2
SCHEMBL11136985 0.77 HTR6 (0.41) TDP1HSD17B10ALDH1A1L3MBTL1CA2
SCHEMBL9165551 0.75 ALDH1A1 (0.48) TDP1HSD17B10ALDH1A1CDK2TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112354374-B High-interception seawater desalination composite reverse osmosis membrane, preparation method and application 天津工业大学 2022-08-12 CN claimed
CN-112354374-A High-interception seawater desalination composite reverse osmosis membrane, preparation method and application 天津工业大学 2021-02-12 CN claimed
CN-118437153-B Reverse osmosis composite membrane and preparation method and application thereof 山东招金膜天股份有限公司 2024-10-18 CN disclosed
CN-118437153-A Reverse osmosis composite membrane and preparation method and application thereof 山东招金膜天股份有限公司 2024-08-06 CN disclosed
CN-112354374-B High-interception seawater desalination composite reverse osmosis membrane, preparation method and application 天津工业大学 2022-08-12 CN disclosed
CN-112354374-A High-interception seawater desalination composite reverse osmosis membrane, preparation method and application 天津工业大学 2021-02-12 CN disclosed